Shikuma, Cecilia MD

Selected Publications

• Chang DA, Ede RC, Chow DC, Souza RD, Gangcuangco LM, Hanks N, Nakamoto BK, Mitchell B, Masutani AT, Fisk S, Shikuma CM, Dill JE.
  Early Childhood Vision Screening in Hawai'i Utilizing a Hand-Held Screener.
  Hawaii J Med Public Health 2015 [more...]


• Chow D, Nakamoto BK, Sullivan K, Sletten DM, Fujii S, Umekawa S, Kocher M, Kallianpur KJ, Shikuma CM, Low P.
  Symptoms of Autonomic Dysfunction in Human Immunodeficiency Virus.
  Open Forum Infect Dis 2015 [more...]


• Chow D, Young R, Valcour N, Kronmal RA, Lum CJ, Parikh NI, Tracy RP, Budoff M, Shikuma CM.
  HIV and coronary artery calcium score: comparison of the Hawaii Aging with HIV Cardiovascular Study and Multi-Ethnic Study of Atherosclerosis (MESA) cohorts.
  HIV Clin Trials 2015 [more...]


• Kocher MH, Hetzler RK, Shikuma CM, Kimura IF, Stickley CD, Lindsey RA, Nakamoto BK, Chow DC.
  Autonomic Function is Associated with Fitness Level in HIV-Infected Individuals.
  Jacobs J AIDS HIV 2015 [more...]


• Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN.
  Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.
  AIDS Res Hum Retroviruses 2015 [more...]


• Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM.
  Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort.
  Atherosclerosis 2015 [more...]


• Sentell TL, Valcour N, Ahn HJ, Miyamura J, Nakamoto B, Chow D, Masaki K, Seto TB, Chen JJ, Shikuma C.
  High rates of Native Hawaiian and older Japanese adults hospitalized with dementia in Hawai'i.
  J Am Geriatr Soc 2015 [more...]


• Shikuma CM, Bennett K, Ananworanich J, Gerschenson M, Teeratakulpisarn N, Jadwattanakul T, DeGruttola V, McArthur JC, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiat P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N.
  Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy.
  J Neurovirol 2015 [more...]


• Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM.
  Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.
  Atherosclerosis 2014 [more...]


• Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J, Wendelken L, Desai A, Hutchings N, Chomchey N, Jirajariyavej S, Chaisit P, Chinvarun Y, Thongkramjaroen P, Thongmuang S, Jarupittaya S, Khongtia P, Jadwattanakul T, Methajittiphun P, Mingkwanrungruang P, Chalermchai T, Phanuphak N, Kroon E, Terratakulpisarn N, Suttichom D, Rattanamanee S, Boonchan M.
  HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy.
  AIDS 2014 [more...]


• Ndhlovu LC, Umaki T, Chew GM, Chow DC, Agsalda M, Kallianpur KJ, Paul R, Zhang G, Ho E, Hanks N, Nakamoto B, Shiramizu BT, Shikuma CM.
  Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for...
  J Neurovirol 2014 [more...]


• Sentell T, Marten L, Ahn HJ, Qui Y, Chen JJ, Miyamura J, Chow D, Shikuma C.
  Disparities in hospitalizations among HIV positive individuals for Native Hawaiians and Asians compared to Whites in Hawai'i.
  Hawaii J Med Public Health 2014 [more...]


• Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD.
  Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.
  PLoS One 2014 [more...]


• Shikuma CM, Gangcuangco LM, Killebrew DA, Libutti DE, Chow DC, Nakamoto BK, Liang CY, Milne CI, Ndhlovu LC, Barbour JD, Shiramizu BT, Gerschenson M.
  The role of HIV and monocytes/macrophages in adipose tissue biology.
  J Acquir Immune Defic Syndr 2014 [more...]


• Sullivan K, Shikuma CM, Chow D, Cornelius E, Romine RK, Lindsey RA, Stickley CD, Kimura IF, Hetzler RK.
  Aerobic fitness levels and validation of a non exercise VO2max prediction equation for HIV-infected patients on HAART.
  HIV Clin Trials 2014 [more...]


• Chow D, Nakamoto B, So E, Parikh N, Souza S, Kallianpur K, Shikuma C.
  Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy.
  J Neurovirol 2013 [more...]


• Gangcuangco LM, Chow DC, Liang CY, Nakamoto BK, Umaki TM, Kallianpur KJ, Shikuma CM.
  Predictors of 25-hydroxyvitamin D levels in HIV-infected patients in Hawai'i.
  Hawaii J Med Public Health 2013 [more...]


• Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD.
  IL-1B enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.
  PLoS One 2013 [more...]


• Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N.
  Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter.
  Neurology 2013 [more...]


• Lin C, Grandinetti A, Shikuma C, Souza S, Parikh N, Nakamoto B, Kallianpur KJ, Chow D.
  The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients.
  Hawaii J Med Public Health 2013 [more...]


• Nakamoto BK, Shikuma CM, Ogata-Arakaki D, Umaki T, Neuwelt EA, Shiramizu BT, Chow DC, Parikh NI, Kallianpur KJ, Hamilton BE.
  Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder.
  J Neurovirol 2013 [more...]


• Shikuma CM, McArthur JC, Ebenezer GJ, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Valcour VG, Bennett K, Phanuphak N.
  Ethnic differences in epidermal nerve fiber density.
  Muscle Nerve 2013 [more...]


• Tongma C, Shikuma CM, Nakamoto BK, Kallianpur KJ, Umaki TM, Barbour JD, Ndhlovu L, Parikh NI, Chow DC.
  Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy.
  Hawaii J Med Public Health 2013 [more...]


• Umaki TM, Gangcuangco LM, Chow DC, Nakamoto BK, Marotz L, Kallianpur KJ, Shikuma CM.
  Poorer neuropsychological performance increases risk for social services among HIV-infected individuals.
  Hawaii J Med Public Health 2013 [more...]


• Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B, SEARCH 011 Protocol Team
  HIV DNA reservoir increases risk for cognitive disorders in cART-na�?�¯ve patients.
  PLoS One 2013 [more...]


• Chow D, Kocher M, Shikuma C, Parikh N, Grandinetti A, Nakamoto B, Seto T, Low P.
  Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report.
  Int J Med Sci 2012 [more...]


• Chow D, Thomas BS, Liang CY, Souza SC, Nakamoto BK, Parikh NI, Shikuma C.
  Role of the veterans aging cohort study index in assessing total atherosclerotic burden.
  Clin Infect Dis 2012 [more...]


• Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C.
  Regional cortical thinning associated with detectable levels of HIV DNA.
  Cereb Cortex 2012 [more...]


• Kusao I, Shiramizu B, Liang CY, Grove J, Agsalda M, Troelstrup D, Velasco VN, Marshall A, Whitenack N, Shikuma C, Valcour V.
  Cognitive performance related to HIV-1-infected monocytes.
  J Neuropsychiatry Clin Neurosci 2012 [more...]


• Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM.
  Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals.
  J Neurovirol 2012 [more...]


• Shikuma C, Gerschenson M, Ananworanich J, Valcour V, Teeratakulpisarn N, Jadwattanakul T, Degruttola V, Liang CY, McArthur J, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiath P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N.
  Determinants of epidermal nerve fibre density in antiretroviral-na�¯ve HIV-infected individuals.
  HIV Med 2012 [more...]


• Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG.
  Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.
  Antivir Ther 2012 [more...]


• Shikuma CM, Seto T, Liang CY, Bennett K, DeGruttola V, Gerschenson M, Stein JH, Budoff M, Hodis HN, Delaney JA, Ogata-Arakaki D, Pramyothin P, Chow D.
  Vitamin D levels and markers of arterial dysfunction in HIV.
  AIDS Res Hum Retroviruses 2012 [more...]


• Shiramizu B, Ananworanich J, Chalermchai T, Siangphoe U, Troelstrup D, Shikuma C, De Grutolla V, Sithinamsuwan P, Praihirunkit P, Rattanamanee S, Valcour V, Nidhinandana S, Thitivichianlert S, Chuenchitra T, Sukwit S, Chitpatima S, Apateerapong W, Boonchokchai B, Watt G, Suttichom D, Chomchey N, Velasco VN, Trichavaroj R.
  Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy.
  J Neurovirol 2012 [more...]


• Chow DC, Wood R, Choi J, Grandinetti A, Gerschenson M, Sriratanaviriyakul N, Nakamoto B, Shikuma C, Low P.
  Cardiovagal autonomic function in HIV-infected patients with unsuppressed HIV viremia.
  HIV Clin Trials 2011 [more...]


• Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM.
  Impact of cerebrovascular disease on cognitive function in HIV-infected patients.
  J Acquir Immune Defic Syndr 2011 [more...]


• Payam A, Shiramizu B, Shikuma C, Milne C, Terada K, Kajioka E, Ka'opua LS, Cassel K, Chow D.
  HIV-associated anal dysplasia: experience from a multiethnic-HIV clinic in Hawaii.
  J Health Care Poor Underserved 2011 [more...]


• Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C.
  The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort.
  World J AIDS 2011 [more...]


• Nakamoto BK, McMurtray A, Davis J, Valcour V, Watters MR, Shiramizu B, Chow DC, Kallianpur K, Shikuma CM.
  Incident neuropathy in HIV-infected patients on HAART.
  AIDS Res Hum Retroviruses 2010 [more...]


• Valcour VG, Shiramizu BT, Shikuma CM.
  HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications.
  J Leukoc Biol 2010 [more...]


• Chow DC, Tasaki A, Ono J, Shiramizu B, Souza SA.
  Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome.
  Biologics 2008 [more...]


• McMurtray A, Nakamoto B, Shikuma C, Valcour V.
  Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study.
  J Stroke Cerebrovasc Dis 2008 [more...]