Publication Detail

Citation : Laczko R, Szauter KM, Csiszar K. (2014)
LOXL1-associated candidate epithelial pathomechanisms in exfoliation glaucoma.
J Glaucoma 23(8 Suppl 1):S43-7.
Abstract : Results of the present study support ocular epithelia-specific LOXL1 functions in exfoliation glaucoma that may include both dysregulated extracellular matrix cross-linking activity and cellular mechanisms involving a role for LOXL1, in direct interaction with Snail1, in promoting epithelial to mesenchymal transition and a potential shift towards fibrogenic epithelial cell phenotypes.
URL Link : http://www.ncbi.nlm.nih.gov/pubmed/25275905
PMID : 25275905
PMCID : PMC4205763
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